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What is DNA Sequencing?

Proceedings of the National Academy of Sciences. Metzker ML. Sequencing technologies-the next generation. Nature reviews genetics. Lohmann K, Klein C. Next generation sequencing and the future of genetic diagnosis. Next generation sequencing: implications in personalized medicine and pharmacogenomics. Mol Biosyst. Next-generation sequencing in the clinic: promises and challenges.

Cancer letters.

RNA-seq: Basics, Applications and Protocol | Technology Networks

Chang F, Li MM. Clinical application of amplicon-based next-generation sequencing in cancer. Cancer genetics. Comparison of next-generation sequencing systems. BioMed Research International.

Gene Sequencing & Haplotyping

Milos PM. Emergence of single-molecule sequencing and potential for molecular diagnostic applications. Expert review of molecular diagnostics.

Single-molecule DNA sequencing of a viral genome. Chial H. Mendelian genetics: patterns of inheritance and single-gene disorders. Nature Education. Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disorders. Journal of human genetics.

Clinical application of next-generation sequencing for Mendelian diseases. Hum Genomics. Rehm HL. Disease-targeted sequencing: a cornerstone in the clinic. Nat Rev Genet. Whole genome sequencing. Genetic Variation: Springer; Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing.

Nature genetics. Genetic prediction of common complex disorders assessed by next generation sequencing and genome wide analysis. Italian Journal of Public Health. On the allelic spectrum of human disease. The structure of haplotype blocks in the human genome. Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip.

Services on Demand

PLoS Genet. The Clinical Biochemist Reviews. International network of cancer genome projects. Cancer cell. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. The molecular pathology of cancer. Nature reviews Clinical oncology.

DNA Sequencing - 3D

A window into third-generation sequencing. Human molecular genetics.


  • Back to Basics: Next-generation sequencing methods and applications.
  • Sideshow (Arbai, Book 3).
  • Graphene and DNA sequencing: introduction and market status | Graphene-Info.
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Shendure J, Ji H. Next-generation DNA sequencing. Nature biotechnology. Glenn TC. Molecular ecology resources. Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations. Genome sequencing in microfabricated high-density picolitre reactors. Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding. Genome research. Accurate whole human genome sequencing using reversible terminator chemistry. A sequencing method based on real-time pyrophosphate.

Epigenetics: a landscape takes shape. Bird A. Perceptions of epigenetics. Epigenetic Modifications Regulate Gene Expression. Jenuwein T, Allis CD.

Whole genome sequencing of bacterial genomes - tools and applications

Translating the histone code. Berger SL.

The complex language of chromatin regulation during transcription. Kouzarides T. Chromatin modifications and their function. Mechanisms of disease: the developmental origins of disease and the role of the epigenotype.


  1. DNA sequencing.
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  3. Managing Risk in Organizations: A Guide for Managers.
  4. Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Feinberg AP, Tycko B. The history of cancer epigenetics. Nature Reviews Cancer. Esteller M. Epigenetics in cancer.

    INTRODUCTION

    New England Journal of Medicine. DNA methylation in the pathogenesis of autoimmunity.